Improving survival rates for adolescents and young adults with cancer.
One of the challenges for the adolescent and young adult (AYA) cancer population is the transition of adolescent cancer survivors treated at pediatric institutions to adult-based providers in their young adult years. Unfortunately, most AYA survivors are not enrolled and followed in survivorship programs and are oftentimes treated by primary care physicians who are unfamiliar with AYA cancers and the long-term effects and issues associated with them.
Source: Closing the Gap: Research and Care Imperatives for Adolescents and Young Adults with Cancer, Report of the Adolescent and Young Adult Oncology Progress Review Group. U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, National Institutes of Health, National Cancer Institute, LIVESTRONG™ Young Adult Alliance; NIH Pub. 06-6067; 2006.
Transitioning childhood cancer survivors to adult-centered healthcare: insights from parents, adolescent, and young adult survivors.
Psychooncology. 2010 Sep;19(9):982-90
Authors: Casillas J, Kahn KL, Doose M, Landier W, Bhatia S, Hernandez J, Zeltzer LK,
To determine Latino adolescent and young adults (AYA) cancer survivors' perceived barriers or facilitators to transition from pediatric to adult-centered survivorship care and to also assess the parents' perspective of care.
PMID:...
The meaning of surviving cancer for Latino adolescents and emerging young adults.
Cancer Nurs. 2010 Jan-Feb;33(1):74-81
Authors: Jones BL, Volker DL, Vinajeras Y, Butros L, Fitchpatrick C, Rossetto K
Adolescent and young adult (AYA) survivors of cancer are an understudied population with unique developmental and medical needs that extend well beyond their active treatment. Survivors diagnosed as AYAs...
A comparison of clinical trial enrollment between adolescent and young adult (AYA) oncology patients treated at affiliated adult and pediatric oncology centers.
J Pediatr Hematol Oncol. 2009 Dec;31(12):927-9
Authors: Downs-Canner S, Shaw PH
Over the past 30 years, there has been a dramatic increase in the survival rates of younger pediatric cancer patients in contrast to adolescent and young adult (AYA) oncology patients. The reasons for this discrepancy are multifactorial, but it is clear that...
Acute lymphoblastic leukemia in adolescents and young adults.
Hematol Oncol Clin North Am. 2009 Oct;23(5):1033-42, vi
Authors: Ribera JM, Oriol A
Today, long-term survival is achieved in more than 80% of children 1 to 10 years old with acute lymphoblastic leukemia (ALL). However, cure rates for adults and adolescents and young adults (AYA) with ALL remain relatively low, at only 40% to 50%. Age is a continuous prognostic variable in ALL, with no single age at which prognosis deteriorates markedly....
Adolescents & young adults: issues in transition from active therapy into follow-up care.
Eur J Oncol Nurs. 2009 Jul;13(3):207-12
Authors: Thompson K, Palmer S, Dyson G
The development of services focused on addressing the needs of Adolescent & Young Adult (AYA) cancer patients as they transition from active therapy into follow-up care is an area of growth, development and research across the globe. This is important as much of the empirical literature and service development to date has...
The unique characteristics of ovarian carcinogenesis in the adolescent and young adult population.
Semin Oncol. 2009 Jun;36(3):250-7
Authors: Gibbon DG, Diaz-Arrastia C
Ovarian cancer in the adolescent and young adult (AYA) population is a disease that is distinctly different with regard to risk factors, genetics, and pathology when compared to ovarian cancers occurring in older women. This article will review the theories behind ovarian carcinogenesis and attempt to elucidate why these tumors...
Proteomic-based detection of a protein cluster dysregulated during cardiovascular development identifies biomarkers of congenital heart defects.
PLoS One. 2009;4(1):e4221
Authors: Nath AK, Krauthammer M, Li P, Davidov E, Butler LC, Copel J, Katajamaa M, Oresic M, Buhimschi I, Buhimschi C, Snyder M, Madri JA
Cardiovascular development is vital for embryonic survival and growth. Early gestation embryo...
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