Improving survival rates for adolescents and young adults with cancer.
One of the challenges for the adolescent and young adult (AYA) cancer population is the transition of adolescent cancer survivors treated at pediatric institutions to adult-based providers in their young adult years. Unfortunately, most AYA survivors are not enrolled and followed in survivorship programs and are oftentimes treated by primary care physicians who are unfamiliar with AYA cancers and the long-term effects and issues associated with them.
Source: Closing the Gap: Research and Care Imperatives for Adolescents and Young Adults with Cancer, Report of the Adolescent and Young Adult Oncology Progress Review Group. U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES, National Institutes of Health, National Cancer Institute, LIVESTRONG™ Young Adult Alliance; NIH Pub. 06-6067; 2006.
Usefulness of the hematopoietic cell transplantation-specific comorbidity index (HCT-CI) in predicting outcomes for adolescents and young adults with hematologic malignancies undergoing allogeneic stem cell transplant.
Pediatr Blood Cancer. 2011 Sep;57(3):499-505
Authors: Wood W, Deal A, Whitley J, Sharf A, Serody J, Gabriel D, Shea T
The HCT-CI helps to predict non-relapse mortality (NRM) and overall survival (OS) in allogeneic hematopoietic cell transplantation (HCT) recipients. The usefulness of...
Music's relevance for adolescents and young adults with cancer: a constructivist research approach.
Support Care Cancer. 2011 Feb 11;
Authors: O'Callaghan C, Barry P, Thompson K
PURPOSE: Music is one of the most widely used activities amongst young people, significant in personal and group identity, motivation, physical release, and emotional support. Adolescents and young adults with cancer (AYA) require specialized care because of intensified challenges related to developmental vulnerability,...
Recruitment and follow-up of adolescent and young adult cancer survivors: the AYA HOPE Study.
J Cancer Surviv. 2011 Jan 28;
Authors: Harlan LC, Lynch CF, Keegan TH, Hamilton AS, Wu XC, Kato I, West MM, Cress RD, Schwartz SM, Smith AW, Deapen D, Stringer SM, Potosky AL,
INTRODUCTION: Cancer is rare in adolescents and young adults (AYA), but these patients have seen little improvement in survival in contrast to most other age groups. Furthermore, participation in research by AYAs is typically low. We...
Clinical and molecular features of papillary thyroid cancer in adolescents and young adults.
Cancer. 2011 Jan 15;117(2):259-67
Authors: Vriens MR, Moses W, Weng J, Peng M, Griffin A, Bleyer A, Pollock BH, Indelicato DJ, Hwang J, Kebebew E
Age disparities in thyroid cancer incidence and outcome among adolescents and young adults (AYAs) with thyroid cancer are under reported. In this study, the authors compared the molecular and clinical features of papillary thyroid cancer (PTC) in AYAs with the...
Socioeconomic Impacts on Survival Differ by Race/Ethnicity among Adolescents and Young Adults with Non-Hodgkin's Lymphoma.
J Cancer Epidemiol. 2010;2010:824691
Authors: Kent EE, Morris RA, Largent JA, Ziogas A, Sender LS, Anton-Culver H
Shorter survival has been associated with low socioeconomic status (SES) among elderly non-Hodgkin's lymphoma (NHL) patients; however it remains unknown whether the same...
The unique characteristics of ovarian carcinogenesis in the adolescent and young adult population.
Semin Oncol. 2009 Jun;36(3):250-7
Authors: Gibbon DG, Diaz-Arrastia C
Ovarian cancer in the adolescent and young adult (AYA) population is a disease that is distinctly different with regard to risk factors, genetics, and pathology when compared to ovarian cancers occurring in older women. This article will review the theories behind ovarian carcinogenesis and attempt to elucidate why these tumors...
Recruitment of adolescents and young adults to cancer clinical trials--international comparisons, barriers, and implications.
Semin Oncol. 2010 Apr;37(2):e1-8
Authors: Fern LA, Whelan JS
The last 30 years have seen significant improvements in survival rates for children and older adults. In contrast, the 5-year survival rate among 20 to 39 year olds has been static at around 70% since 1986. Data from the United States, Australia, Italy, and the United Kingdom suggest that this age group also has...
Psychological outcomes and health beliefs in adolescent and young adult survivors of childhood cancer and controls.
J Clin Oncol. 2010 Apr 20;28(12):2002-7
Authors: Kazak AE, Derosa BW, Schwartz LA, Hobbie W, Carlson C, Ittenbach RF, Mao JJ, Ginsberg JP
PURPOSE The purpose of this study was to compare adolescent and young adult (AYA) pediatric cancer survivors and peers without a history of serious...
Evaluation of a survivorship educational program for adolescent and young adult survivors of childhood cancer.
J Cancer Educ. 2010 Dec;25(4):530-7
Authors: Bingen K, Kupst MJ
Educational programs to address specific needs of adolescent and young adult (AYA) childhood cancer survivors are scarce. A quarterly speaker series and 1-day conference involved presentations by oncology experts to increase knowledge of AYA cancer survivorship issues and awareness of community programs and resources. Pre- and...
Intraspecific competition between co-infecting parasite strains enhances host survival in African trypanosomes.
Ecology. 2009 Dec;90(12):3367-78
Authors: Balmer O, Stearns SC, Schötzau A, Brun R
It is becoming increasingly clear that under natural conditions parasitic infections commonly consist of co-infections with multiple conspecific strains. Multiple-strain infections lead to intraspecific interactions and may have important ecological and evolutionary effects on both hosts and parasites....
Transitioning childhood cancer survivors to adult-centered healthcare: insights from parents, adolescent, and young adult survivors.
Psychooncology. 2010 Sep;19(9):982-90
Authors: Casillas J, Kahn KL, Doose M, Landier W, Bhatia S, Hernandez J, Zeltzer LK,
To determine Latino adolescent and young adults (AYA) cancer survivors' perceived barriers or facilitators to transition from pediatric to adult-centered survivorship care and to also assess the parents' perspective of care.
PMID:...
The meaning of surviving cancer for Latino adolescents and emerging young adults.
Cancer Nurs. 2010 Jan-Feb;33(1):74-81
Authors: Jones BL, Volker DL, Vinajeras Y, Butros L, Fitchpatrick C, Rossetto K
Adolescent and young adult (AYA) survivors of cancer are an understudied population with unique developmental and medical needs that extend well beyond their active treatment. Survivors diagnosed as AYAs...
from patients, caregivers and medical professionals dealing with this disease and many other diseases
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