A chief concern affecting quality of life among young adult (YA) cancer survivors is fertility. Although discussions regarding the possibility of infertility and methods to decrease the risk are crucial at the time of diagnosis, many YAs don’t remember having adequate discussions regarding these topics before the initiation of their treatment. Embryo cryopreservation in women and sperm cryopreservation in men before cancer therapy remains to be the most effective ways in which fertility is preserved in the YA population. Although female and male gonadal tissue cryopreservation and transplantation remain experimental, such options are explored and continuously researched through programs such as the Oncofertility Consortium at Northwestern University.
Sources: Levine J, Canada A, Stern C. Fertility Preservation in Adolescents and Young Adults With Cancer. J Clin Oncol. 2010; 28:4831-4841.
Bleyer A, Barr R. Cancer in Young Adults 20 to 39 Years of Age: Overview. Semin Oncol. 2009; 36:194-206.
Minimal residual disease of leukemia and the quality of cryopreserved human ovarian tissue in vitro.
Leuk Lymphoma. 2016;57(3):700-7
Authors: Asadi-Azarbaijani B, Sheikhi M, Nurmio M, Tinkanen H, Juvonen V, Dunkel L, Hovatta O, Oskam IC, Jahnukainen K
Fertility in young patients following treatment for Hodgkin's lymphoma: a single center survey.
J Assist Reprod Genet. 2016 Mar;33(3):325-33
Authors: Boltežar L, Pintarić K, Jezeršek Novaković B
Semen cryopreservation and usage rate for assisted reproductive technology in 898 men with cancer.
Reprod Biomed Online. 2016 Feb;32(2):147-53
Authors: Muller I, Oude Ophuis RJ, Broekmans FJ, Lock TM
An undesired side effect of cancer...
Is Ovarian Preservation Feasible in Early-Stage Adenocarcinoma of the Cervix?
Med Sci Monit. 2016 Feb 08;22:408-14
Authors: Lu H, Li J, Wang L, Zhou H, Liu Y, Wang D, Lin Z
BACKGROUND In cervical adenocarcinoma, surgical treatment involves bilateral...
Is there a justification for hysterectomy in patients with borderline ovarian tumors?
Surg Oncol. 2016 Mar;25(1):1-5
Authors: Ouldamer L, Lacoste C, Cormier B, Arbion F, Marret H, Jallais L, Fignon A, Body G
OBJECTIVE: To determine the...
Effects of Angiopoietin-2 on Transplanted Mouse Ovarian Tissue.
PLoS One. 2016;11(11):e0166782
Authors: Youm HW, Lee J, Kim EJ, Kong HS, Lee JR, Suh CS, Kim SH
Transplantation of ovarian tissue (OT) is currently the only clinical option to restore fertility...
Physicians' practice of discussing fertility preservation with cancer patients and the associated attitudes and barriers.
Support Care Cancer. 2016 Nov 26;
Authors: Takeuchi E, Kato M, Wada S, Yoshida S, Shimizu C, Miyoshi Y
PURPOSE: The aim of this study is to...
Do Patient Characteristics Decide if Young Adult Cancer Patients Undergo Fertility Preservation?
J Adolesc Young Adult Oncol. 2016 Nov 28;
Authors: Flink DM, Sheeder J, Kondapalli LA
PURPOSE: The Fertility Attitudes and Cancer Treatment Study (FACTS) is a two-phase research initiative aimed to understand factors...
Debated Role of Ovarian Protection With Gonadotropin-Releasing Hormone Agonists During Chemotherapy for Preservation of Ovarian Function and Fertility in Women With Cancer.
J Clin Oncol. 2016 Nov 28;:JCO2016692582
Authors: Lambertini M, Falcone T, Unger JM, Phillips KA, Del Mastro L, Moore HC
PMID: 27893335 [PubMed - as supplied by publisher...
SEOM Clinical Guideline of fertility preservation and reproduction in cancer patients (2016).
Clin Transl Oncol. 2016 Dec;18(12):1229-1236
Authors: Muñoz M, Santaballa A, Seguí MA, Beato C, de la Cruz S, Espinosa J, Fonseca PJ, Perez J, Quintanar T, Blasco A
Fertility Preservation in Pediatric and Adolescent Oncology Patients: The Decision-Making Process of Parents.
J Adolesc Young Adult Oncol. 2016 Dec 01;
Authors: Li N, Jayasinghe Y, Kemertzis MA, Moore P, Peate M
PURPOSE: Decisions surrounding fertility preservation (FP) in children, adolescents, and adults can be...
Teenagers with cancer need access to fertility preservation services, urges nurse expert.
Nurs Child Young People. 2016 Dec 08;28(10):7
A leading fertility nurse has said young people with cancer must be offered access to fertility treatment.
PMID: 27927110 [PubMed - in process]
from patients, caregivers and medical professionals dealing with this disease and many other diseases