A chief concern affecting quality of life among young adult (YA) cancer survivors is fertility. Although discussions regarding the possibility of infertility and methods to decrease the risk are crucial at the time of diagnosis, many YAs don’t remember having adequate discussions regarding these topics before the initiation of their treatment. Embryo cryopreservation in women and sperm cryopreservation in men before cancer therapy remains to be the most effective ways in which fertility is preserved in the YA population. Although female and male gonadal tissue cryopreservation and transplantation remain experimental, such options are explored and continuously researched through programs such as the Oncofertility Consortium at Northwestern University.
Sources: Levine J, Canada A, Stern C. Fertility Preservation in Adolescents and Young Adults With Cancer. J Clin Oncol. 2010; 28:4831-4841.
Bleyer A, Barr R. Cancer in Young Adults 20 to 39 Years of Age: Overview. Semin Oncol. 2009; 36:194-206.
Management of Early Invasive Breast Cancer in Very Young Women (<35 years).
Clin Breast Cancer. 2011 Jul 11;
Authors: Hartmann S, Reimer T, Gerber B
BACKGROUND: To give an overview about current treatment recommendations and special problems concerning the management of women <35 years with early breast cancer. METHODS: We performed a selective systematic literature review. We discussed with reference to key studies and meta-analyses, current standards of care, and controversies regarding...
Discussing fertility preservation options with patients with cancer.
JAMA. 2011 Jul 13;306(2):202-3
Authors: Snyder KA, Pearse W
PMID: 21750299 [PubMed - indexed for MEDLINE]
Fertility determinants after conservative surgery for mucinous borderline tumours of the ovary (excluding peritoneal pseudomyxoma).
Hum Reprod. 2011 Apr;26(4):808-14
Authors: Koskas M, Uzan C, Gouy S, Pautier P, Lhommé C, Haie-Meder C, Duvillard P, Morice P
BACKGROUND The aim of this study was to define determinants of fertility in patients treated conservatively for mucinous borderline ovarian tumours (MBOTs), and to compare outcomes after salpingo-oophorectomy or cystectomy. METHODS This was a...
Surgery of ovarian tumors in children.
Horm Res Paediatr. 2011;75(3):220-4
Authors: Sarnacki S, Brisse H
Surgery of ovarian tumors in children requires a good knowledge of these lesions. Complete resection is mandatory for malignant lesions, and in the case of benign tumors preservation of healthy ovarian tissue is crucial. Diagnosis is based on clinical features (age and hormonal status), imaging and tumor marker levels. Laparoscopy is of great help in making a diagnosis and staging when the...
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