Almost one third of all new thyroid cancers diagnosed are in young adults ages 20 to 40 and thyroid carcinomas represent approximately 6-12% of all malignancies diagnosed in this age group. Thyroid carcinomas are 5 times more common in females than males among 20 to 40 year olds, accounting for 4% of all cancers in women. Thyroid cancer is also one of the most common malignancies to occur during pregnancy and therefore it is imperative to assess the treatment and management of such cases individually with possible delay in surgery and radioactive iodine therapy. Overall survival rates are exceptional with 5-year survival rates for individuals diagnosed before the age of 40 above 99%. Future research will hopefully shed light to understanding the long-term and potentially adverse effects of different thyroid treatment therapies as well as their effects on reproduction, which may impact the survivorship of this community.
Source: Ying A, Huh W, Bottomley S, et al. Thyroid Cancer in Young Adults. Semin Oncol. 2009; 36:258-274.
Pediatric, Adolescent, and Young Adult Thyroid Carcinoma Harbors Frequent and Diverse Targetable Genomic Alterations, Including Kinase Fusions.
Oncologist. 2017 Mar;22(3):255-263
Authors: Vanden Borre P, Schrock AB, Anderson PM, Morris JC, Heilmann AM, Holmes O...
Lymph node characteristics for predicting locoregional recurrence of papillary thyroid cancer in adolescents and young adults.
Oral Oncol. 2017 Mar;66:22-27
Authors: Sun Y, Liu X, Ouyang W, Feng H, Wu J, Chen P, Wang J
[Characteristics of Adolescent and Young Adult Cancer].
Gan To Kagaku Ryoho. 2017 Jan;44(1):7-11
Authors: Horibe K
In adolescent and young adult(AYA)population, cancer is the leading cause of death due to illness with...
[Specificities of carcinomas in adolescents and young adults].
Bull Cancer. 2016 Dec 15;:
Authors: Fresneau B, Dourthe ME, Jouin A, Laurence V, de Lambert G, Colas C, Coret M, Laprie A, Rebours C, Orbach D, Demoor-Goldschmidt C
[Cancer in adolescents and young adults in France: Epidemiology and pathways of care].
Bull Cancer. 2016 Nov 3;:
Authors: Desandes E, Lacour B, Clavel J, le Réseau français des registres de cancers
In adolescents and young adults (AYA),...
Prevalence and correlates of fear of recurrence among adolescent and young adult versus older adult post-treatment cancer survivors.
Support Care Cancer. 2016 Jul 7;
Authors: Shay LA, Carpentier MY, Vernon SW
PURPOSE: We sought to (1) assess prevalence of fear of...
Age at Primary Malignancy Determines Survival in Adolescent and Young Adults That Develop a Secondary Thyroid Cancer.
J Adolesc Young Adult Oncol. 2016 Apr 4;
Authors: Lau BJ, Goldfarb M
PURPOSE: Second malignancy status is a risk factor for death in adolescent and young adults (AYAs) (ages 15-39) with thyroid cancer (TC...
Incidence and incidence trends of the most frequent cancers in adolescent and young adult Americans, including "nonmalignant/noninvasive" tumors.
Cancer. 2016 Feb 5;
Authors: Barr RD, Ries LA, Lewis DR, Harlan LC, Keegan TH, Pollock BH, Bleyer WA, US...
Comparison of cancer survival trends in the United States of adolescents and young adults with those in children and older adults.
Cancer. 2016 Feb 5;
Authors: Keegan TH, Ries LA, Barr RD, Geiger AM, Dahlke DV, Pollock BH, Bleyer A, National Cancer...
An analysis of discrepancies between United Kingdom cancer research funding and societal burden and a comparison to previous and United States values.
Health Res Policy Syst. 2015;13:62
Increased risk of second malignant neoplasms in adolescents and young adults with cancer.
Cancer. 2015 Oct 6;
Authors: Lee JS, DuBois SG, Coccia PF, Bleyer A, Olin RL, Goldsby RE
BACKGROUND: The authors describe the...
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