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Liver Cancer

Primary liver neoplasms account for only 1% of all neoplasms in young people ages 15-29 with heptaocellular carcinomas (HCCs) being the most common liver tumor seen in adolescents and young adults (AYA). The leading cause of HCC in AYAs in Asia and Africa is chronic infection from hepatitis B virus while in Western countries less than a third of AYAs develop HCC from hepatitis or other inflammatory liver diseases. Patients less than 15 years of age have an overall survival of approximately 60%, dropping to 16% for those ages 15-29, and continuing to decrease with age. Future research aims include international collaboration between pediatric and adult care facilities to conduct trials for AYAs with HCC.

Source: http://books.google.com/books?id=pXgDooG8SEsC&dq=cancer+in+adolescents+a... Chapt. 19, pgs 311-325.

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Fertility Preservation for AYA Cancers - For Men 15-39, frequent cause of impaired fertility is chemotherapy or radiation damage to sperm. Female survivors may be impaired by treatment that damages immature eggs, affects hormonal balance, or injures reproductive organs. Fertility guidelines: http://www.cancer.gov/ncicancerbulletin/011111/page5

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