Approximately 43,000 men and women were diagnosed with leukemia in the United States in 2009. The disease is unique in that it is common in both pediatric (<15) cancer patients and in older adult (>60) cancer patients. Of those diagnosed with leukemia, approximately 2600, or six percent, were diagnosed as adolescents or young adults (AYAs). Although there have been vast improvements in survival rates especially for pediatric leukemia, AYAs have not seen these same advancements. AYAs are often caught in the gap between pediatrics and adult cancers and different outcomes were seen in comparing treatments based on pediatric protocols versus adult protocols. Overall, adolescents treated on more aggressive pediatric protocols had improved overall and event-free survival.
Source: Advani A, Hunger S, Burnett A, Acute Leukemia in Adolescents and Young Adults. Semin Oncol. 2009; 36:213-226.
Cardiovascular Disease Risk Profiles in Survivors of Adolescent and Young Adult (AYA) Cancer: The Kaiser Permanente AYA Cancer Survivors Study.
J Clin Oncol. 2016 Mar 7;
Authors: Chao C, Xu L, Bhatia S, Cooper R, Brar S, Wong FL, Armenian SH
Social Media and the Adolescent and Young Adult (AYA) Patient with Cancer.
Curr Hematol Malig Rep. 2016 Feb 18;
Authors: Perales MA, Drake EK, Pemmaraju N, Wood WA
Over 70,000 adolescent and young adults (AYA) aged 15 to 39 years are diagnosed with cancer each...
Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes.
Oncotarget. 2016 Feb 12;
Authors: Messina M, Chiaretti S, Wang J, Fedullo AL, Peragine N, Gianfelici V, Piciocchi A, Brugnoletti F, Di Giacomo F,...
[Retrospective Analysis of the Impact of Treatment on Prognosis in 44 Adolescents and Young Adult Patients with Acute Lymphoblastic Leukemia].
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2016 Feb;24(1):14-8
Authors: Chen XP, Lv N, Li YH, Jing Y, Yu L
OBJECTIVE: To study the clinical characteristics and the impact of treatment on...
Is the Adolescent and Young Adult Cancer Survivor at Risk for Late Effects? It Depends on Where You Look.
J Adolesc Young Adult Oncol. 2016 Feb 17;
Authors: Barthel EM, Spencer K, Banco D, Kiernan E, Parsons S
PURPOSE: The adolescent and young adult (AYA) population is a growing group of survivors, exceeding more than...
Biologic and clinical characteristics of adolescent and young adult cancers: Acute lymphoblastic leukemia, colorectal cancer, breast cancer, melanoma, and sarcoma.
Cancer. 2016 Feb 5;
Authors: Tricoli JV, Blair DG, Anders CK, Bleyer A, Boardman LA, Khan J...
Comparison of cancer survival trends in the United States of adolescents and young adults with those in children and older adults.
Cancer. 2016 Feb 5;
Authors: Keegan TH, Ries LA, Barr RD, Geiger AM, Dahlke DV, Pollock BH, Bleyer A, National Cancer...
Incidence and incidence trends of the most frequent cancers in adolescent and young adult Americans, including "nonmalignant/noninvasive" tumors.
Cancer. 2016 Feb 5;
Authors: Barr RD, Ries LA, Lewis DR, Harlan LC, Keegan TH, Pollock BH, Bleyer WA, US...
Patient Characteristics and Outcomes in Adolescents and Young Adults (AYA) With Acute Myeloid Leukemia (AML).
Clin Lymphoma Myeloma Leuk. 2016 Jan 5;
Authors: Pemmaraju N, Kantarjian H, Ravandi F, Nogueras-Gonzalez GM, Huang X, O'Brien S, Wierda W, Garcia-Manero G, Thomas D,...
Psychological morbidities in adolescent and young adult blood cancer patients during curative-intent therapy and early survivorship.
Cancer. 2016 Jan 7;
Authors: Muffly LS, Hlubocky FJ, Khan N, Wroblewski K, Breitenbach K, Gomez J, McNeer JL, Stock W,...
Providing Information About Late Effects During Routine Follow-Up Consultations Between Pediatric Oncologists and Adolescent Survivors: A Video-Based, Observational Study.
J Adolesc Young Adult Oncol. 2015;4(4):200-8
Authors: Mellblom AV, Korsvold L, Finset A, Loge J, Ruud E, Lie HC
PURPOSE: Information about late...
An analysis of discrepancies between United Kingdom cancer research funding and societal burden and a comparison to previous and United States values.
Health Res Policy Syst. 2015;13:62
from patients, caregivers and medical professionals dealing with this disease and many other diseases