Approximately 43,000 men and women were diagnosed with leukemia in the United States in 2009. The disease is unique in that it is common in both pediatric (<15) cancer patients and in older adult (>60) cancer patients. Of those diagnosed with leukemia, approximately 2600, or six percent, were diagnosed as adolescents or young adults (AYAs). Although there have been vast improvements in survival rates especially for pediatric leukemia, AYAs have not seen these same advancements. AYAs are often caught in the gap between pediatrics and adult cancers and different outcomes were seen in comparing treatments based on pediatric protocols versus adult protocols. Overall, adolescents treated on more aggressive pediatric protocols had improved overall and event-free survival.
Source: Advani A, Hunger S, Burnett A, Acute Leukemia in Adolescents and Young Adults. Semin Oncol. 2009; 36:213-226.
A review of the management of adults with T-cell acute lymphoblastic leukemia.
Blood. 2017 Jan 23;:
Authors: Marks DI, Rowntree C
T-cell acute lymphoblastic leukemia (ALL) is a rare disease in adults with inferior survival outcomes compared to those seen in pediatric patients. Although potentially curable with about 50...
[Characteristics of Adolescent and Young Adult Cancer].
Gan To Kagaku Ryoho. 2017 Jan;44(1):7-11
Authors: Horibe K
In adolescent and young adult(AYA)population, cancer is the leading cause of death due to illness with...
The positive effect of a dedicated adolescent and young adult fertility program on the rates of documentation of therapy-associated infertility risk and fertility preservation options.
Support Care Cancer. 2017 Feb 02;:
Authors: Lewin J, Ma JM, Mitchell L, Tam S, Puri N, Stephens D, Srikanthan A,...
The Benefits and Burdens of Cancer: A Prospective Longitudinal Cohort Study of Adolescents and Young Adults.
J Palliat Med. 2017 Jan 04;:
Authors: Straehla JP, Barton KS, Yi-Frazier JP, Wharton C, Baker KS, Bona K, Wolfe J, Rosenberg AR
BACKGROUND: Adolescents and early young adults (AYAs) with cancer are at high risk...
Graft-Versus-Host Disease in Adolescents and Young Adults (15-24 Years Old) After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Leukemia in First Complete Remission.
J Adolesc Young Adult Oncol. 2016 Dec 16;
Authors: Vignon M, Andreoli A, Dhédin N, Lengliné E, Masson E, Robin M, Granier C, Larghero J, Schlageter MH, Peffault de Latour R,...
Complete prevalence of malignant primary brain tumors registry data in the United States compared with other common cancers, 2010.
Neuro Oncol. 2016 Dec 29;:
Authors: Zhang AS, Ostrom QT, Kruchko C, Rogers L, Peereboom DM, Barnholtz-Sloan JS
Racial and ethnic disparities in the survival of adolescents and young adults with acute myeloid leukemia: a retrospective study using the US National Cancer Data Base.
Leuk Lymphoma. 2016 Nov 3;:1-6
Authors: Durani U, Go RS
Outcome differences between children and adolescents and young adults with non-Hodgkin lymphoma following stem cell transplantation.
Int J Hematol. 2016 Oct 27;
Authors: Kobayashi R, Mitsui T, Fujita N, Osumi T, Aoki T, Aoki K, Suzuki R, Fukuda T, Miyamoto T, Kato K, Nakamae H, Goto H, Eto T,...
Outcome of Adolescents and Young Adults Compared With Pediatric Patients With Acute Myeloid and Promyelocytic Leukemia.
Clin Lymphoma Myeloma Leuk. 2016 Sep 17;:
Authors: Nasir SS, Giri S, Nunnery S, Martin MG
BACKGROUND: Studies on the...
Risk-Benefit Analysis of Pediatric-Inspired Versus Hyperfractionated Cyclophosphamide, Vincristine, Doxorubicin, and Dexamethasone Protocols for Acute Lymphoblastic Leukemia in Adolescents and Young Adults.
J Adolesc Young Adult Oncol. 2016 Oct 25;
Authors: Guzauskas GF, Villa KF, Vanhove GF, Fisher VL, Veenstra DL
Prog Tumor Res. 2016;43:87-100
Authors: Juliusson G, Hough R
Leukemias are a group of life threatening malignant disorders of the blood and bone marrow. In the adolescent and young adult (AYA) population, the acute leukemias are most prevalent, with...
Epidemiology of Adolescents and Young Adults with Cancer in Europe.
Prog Tumor Res. 2016;43:1-15
Authors: Desandes E, Stark DP
To design the services for adolescents and young adults (AYAs) with cancer, we need to understand the patterns of disease and the other...
from patients, caregivers and medical professionals dealing with this disease and many other diseases