Germ cell tumors are derived from germ cells, reproductive cells normally occurring in the ovary and testis. Although the incidence of germ cell tumors varies with age, cases before the age of 15 are rare and a peak is seen between 20 and 39 years of age. Germ cell tumor represents about 21% of invasive cancer diagnoses and is most common cancer among males ages 20-39. Germ cell tumors of the ovary are seen to have its peak incidence in the AYA population as well, affecting women often in their early 20’s.
Sources: Gibbon D, Diaz-Arrastia C. The Unique Characteristics of Ovarian Carcinogenesis in the Adolescent and Young Adult Population. Semin Oncol. 2009; 36:250-257.
Non-oncology physician visits after diagnosis of cancer in adolescents and young adults.
J Cancer Surviv. 2016 Feb 13;
Authors: Heins MJ, Lorenzi MF, Korevaar JC, McBride ML
PURPOSE: Health care needs of adolescents and young adults (AYAs) with cancer are...
An analysis of discrepancies between United Kingdom cancer research funding and societal burden and a comparison to previous and United States values.
Health Res Policy Syst. 2015;13:62
Pediatric Melanoma and Atypical Melanocytic Neoplasms.
Cancer Treat Res. 2016;167:331-69
Authors: Sreeraman Kumar R, Messina JL, Reed D, Navid F, Sondak VK
Melanoma is uncommon in the pediatric age range, but is increasing in frequency and often presents with...
Genetic abnormalities in adolescents and young adults with neuroblastoma: A report from the Italian Neuroblastoma group.
Pediatr Blood Cancer. 2015 Oct;62(10):1725-32
Authors: Mazzocco K, Defferrari R, Sementa AR, Garaventa A, Longo L, De Mariano M, Esposito MR, Negri F, Ircolò D, Viscardi E, Luksch R, D'...
Who Treats Adolescents and Young Adults with Cancer? A Report from the AYA HOPE Study.
J Adolesc Young Adult Oncol. 2015 Sep 1;4(3):141-150
Authors: Parsons HM, Harlan LC, Schmidt S, Keegan TH, Lynch CF, Kent EE, Wu XC, Schwartz SM, Chu RL, Keel G, Smith AW, AYA HOPE Collaborative Group
Purpose: Physicians play a...
Use of appropriate initial treatment among adolescents and young adults with cancer.
J Natl Cancer Inst. 2014 Nov;106(11)
Authors: Potosky AL, Harlan LC, Albritton K, Cress RD, Friedman DL, Hamilton AS, Kato I, Keegan TH, Keel G, Schwartz SM, Seibel NL, Shnorhavorian M, West MM, Wu XC, AYA HOPE Study Collaborative Group
Prognostic significance of MTOR pathway component expression in neuroendocrine tumors.
J Clin Oncol. 2013 Sep 20;31(27):3418-25
Authors: Qian ZR, Ter-Minassian M, Chan JA, Imamura Y, Hooshmand SM, Kuchiba A, Morikawa T, Brais LK, Daskalova A, Heafield R, Lin X, Christiani DC,...
Trends in incidence of primary cutaneous malignancies in children, adolescents, and young adults: a population-based study.
Pediatr Blood Cancer. 2014 Feb;61(2):211-6
Authors: Senerchia AA, Ribeiro KB, Rodriguez-Galindo C
BACKGROUND: Skin cancer incidence among young...
Medical care in adolescents and young adult cancer survivors: what are the biggest access-related barriers?
J Cancer Surviv. 2014 Jan 10;
Authors: Keegan TH, Tao L, Derouen MC, Wu XC, Prasad P, Lynch CF, Shnorhavorian M, Zebrack BJ, Chu R, Harlan LC, Smith AW, Parsons HM, AYA HOPE Study...
Cancer in adolescents and young adults, Kingston and St Andrew, Jamaica, 1988-2007.
West Indian Med J. 2013 Jan;62(1):21-7
Authors: Gibson TN, Hanchard B, Waugh N, McNaughton D
OBJECTIVE: To determine the distribution of malignancies in adolescents and young adults (AYA; 15 to 29 years) in Jamaica.
The Adolescent and Young Adult With Cancer: State of the Art-Epithelial Cancer.
Curr Oncol Rep. 2013 Jun 11;
Authors: Ferreira CG, de Melo AC, Nogueira-Rodrigues A
The adolescent and young adult (AYA) is defined as a patient of 15 to 39 years of age at initial...
Cancer in adolescents and young adults (15-29 years): a population-based study in the Netherlands 1989-2009.
Acta Oncol. 2012 Sep;51(7):922-33
Authors: Aben KK, van Gaal C, van Gils NA, van der Graaf WT, Zielhuis GA
BACKGROUND: Cancer among...
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