Improving survival rates for adolescents and young adults with cancer.
In 2008, approximately 6% of all new cases of colorectal cancer (CRC) diagnosed occurred before the age of 40 and 3% of those cases diagnosed between the ages of 20 and 40. While CRC is considered rare overall among young adults, the incidence in this population has been increasing over the last 25 years with predisposing factors still unknown. Commonly children and young adults diagnosed with CRC present with symptoms such as abdominal pain, rectal bleeding, involuntary weight loss and a change in bowel habits. Studies have shown there to be a significant delay in the diagnosis of CRC in the young adult population, which may be due to the nonspecific symptoms patients may present with. Combine these delays with unique tumor biology, we may begin to see reasons why young adults present more often with advanced stage diseases.
Source: Zbuk K, Sidebotham E, Bleyer A, et al. Colorectal Cancer in Young Adults. Semin Oncol. 2009; 36:439-450.
Unique characteristics of adolescent and young adult acute lymphoblastic leukemia, breast cancer, and colon cancer.
J Natl Cancer Inst. 2011 Apr 20;103(8):628-35
Authors: Tricoli JV, Seibel NL, Blair DG, Albritton K, Hayes-Lattin B
Each year in the United States, nearly 70 000 individuals between the ages of 15 and 40 years are diagnosed with cancer. Although overall cancer survival rates among pediatric and older adult patients have increased in recent decades, there has been little improvement in...
Fatigue, pain, and functional status during outpatient chemotherapy.
Oncol Nurs Forum. 2010 Mar;37(2):E114-23
Authors: Siefert ML
To examine the relationship of fatigue and pain with functional status and the pattern of the two symptoms' occurrence over time in individuals with cancer who were receiving outpatient chemotherapy. The aims were to describe the levels of fatigue and pain with functional status and the inter-relationships with each other and with demographic and clinical variables over...
Lay representations of cancer prevention and early detection: associations with prevention behaviors.
Prev Chronic Dis. 2010 Jan;7(1):A14
Authors: Sullivan HW, Rutten LJ, Hesse BW, Moser RP, Rothman AJ, McCaul KD
The Common Sense Model of illness representations posits that how people think about an illness affects how they try to prevent the illness. The purpose of this study was to determine whether...
[Clinical case of the month. Krugenberg tumor in pregnancy].
Rev Med Liege. 2008 Jan;63(1):11-3
Authors: Bouguern H, Bouchikhi Ch, Chaara H, Melhouf MA, Banani A
The authors report the observation of a bilateral ovarian tumor in a pregnant woman. The lesion corresponded to a metastasis from a sigmoïd adenocarcinoma.
PMID: 18303679 [PubMed - indexed for MEDLINE]
Very low incidence of microsatellite instability in intraductal papillary-mucinous neoplasm of the pancreas.
Int J Cancer. 2002 Dec 20;102(6):655-9
Authors: Nakata B, Yashiro M, Nishioka N, Aya M, Yamada S, Takenaka C, Ohira M, Ishikawa T, Nishino H, Wakasa K, Seki S, Hirakawa K
Intraductal papillary-mucinous carcinoma (IPMC) of the pancreas, a new entity of pancreatic cancer with a favorable prognosis, has shown a gradual increase in the number of reported cases. Patients with high-frequency...
Synthesis, biological activity and isomerism of guanylate cyclase C-activating peptides guanylin and uroguanylin.
J Pept Res. 1997 Sep;50(3):222-30
Authors: Klodt J, Kuhn M, Marx UC, Martin S, Rösch P, Forssmann WG, Adermann K
Recently, the peptides guanylin and uroguanylin were identified as endogenous ligands of the membrane-bound guanylate cyclase C (GC-C) that is mainly expressed in the intestinal epithelium. In the present study, bioactive guanylin and uroguanylin have been prepared by solid-...
from patients, caregivers and medical professionals dealing with this disease and many other diseases
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