Breast cancer by the age of 40 accounts for more than 40% of all cancers diagnosed among women. Breast cancer survival rates in women under 40 years of age are lower than those seen in older women regardless of disease staging or subtype. When developing treatment plans for young women diagnosed with breast cancer it is important to address fertility issues such as infertility and pregnancy as well as a deeper understanding of the psychosocial issues the patient may be experiencing. Breast development, conservation and reconstruction are also important issues to be considered as they pertain to body image and overall wellbeing. Breast cancer diagnosed at a younger age can present as more biologically aggressive and have worse outcomes than those diagnosed at a later age, which demonstrates the need for clinical trials tailored towards better understanding this age group’s unique biology and increasing overall survival for this young population.
Source: Anders C, Johnson R, Litton J, et al. Breast Cancer Before Age 40 Years. Semin Oncol. 2009; 36:237-249.
Biologic and clinical characteristics of adolescent and young adult cancers: Acute lymphoblastic leukemia, colorectal cancer, breast cancer, melanoma, and sarcoma.
Cancer. 2016 Feb 5;
Authors: Tricoli JV, Blair DG, Anders CK, Bleyer A, Boardman LA, Khan J...
An analysis of discrepancies between United Kingdom cancer research funding and societal burden and a comparison to previous and United States values.
Health Res Policy Syst. 2015;13(1):62
Authors: Carter AJ, Delarosa B...
Increased risk of second malignant neoplasms in adolescents and young adults with cancer.
Cancer. 2015 Oct 6;
Authors: Lee JS, DuBois SG, Coccia PF, Bleyer A, Olin RL, Goldsby RE
BACKGROUND: The authors describe the...
Adolescent and young adult patients with cancer: a milieu of unique features.
Nat Rev Clin Oncol. 2015 May 26;
Authors: Sender L, Zabokrtsky KB
Adolescent and young adult (AYA) patients with cancer are a unique category of patients who, depending on age at time...
Comparison of primary and secondary breast cancers in adolescents and young adults.
Cancer. 2014 Dec 23;
Authors: Sadler C, Goldfarb M
BACKGROUND: Breast cancer is one of the most common cancers in adolescent and young adult (AYA) patients (ages 15-39) and may develop...
If You Did Not Document It, It Did Not Happen: Rates of Documentation of Discussion of Infertility Risk in Adolescent and Young Adult Oncology Patients' Medical Records.
J Oncol Pract. 2014 Dec 30;
Authors: Quinn GP, Block RG, Clayman ML, Kelvin J, Arvey SR, Lee JH, Reinecke J...
Adolescent and young adult cancer survival.
J Natl Cancer Inst Monogr. 2014 Nov;2014(49):228-35
Authors: Lewis DR, Seibel NL, Smith AW, Stedman MR
Adolescent and young adults (AYAs) face challenges in having their cancers...
Fertility after breast cancer treatment.
Eur J Obstet Gynecol Reprod Biol. 2014 Feb;173:13-8
Authors: Kasum M, Beketić-Orešković L, Peddi PF, Orešković S, Johnson RH
In many countries of the developed world, there is an increasing trend...
Breast Cancer in Adolescent and Young Adult Women.
Clin Breast Cancer. 2014 Jun 23;
Authors: Gewefel H, Salhia B
Breast cancer is one of the most frequently diagnosed malignancy among adolescent and young adult (AYA) women, accounting for...
Cancer Incidence and Survival among Adolescents and Young Adults in Korea.
PLoS One. 2014;9(5):e96088
Authors: Moon EK, Park HJ, Oh CM, Jung KW, Shin HY, Park BK, Won YJ
BACKGROUND: In Korea, cancer is the third leading cause of death among adolescents and...
Unmet information and support needs in newly diagnosed thyroid cancer: comparison of adolescents/young adults (AYA) and older patients.
J Cancer Surviv. 2014 Feb 26;
Authors: Goldfarb M, Casillas J
PURPOSE: Thyroid cancer (TC) is the most common cancer in...
Insurance status and distant-stage disease at diagnosis among adolescent and young adult patients with cancer aged 15 to 39 years: National Cancer Data Base, 2004 through 2010.
Cancer. 2014 Jan 28;
Authors: Robbins AS, Lerro CC, Barr RD
BACKGROUND: The percentage of...
from patients, caregivers and medical professionals dealing with this disease and many other diseases